Phytochemical Screening of Muntingia Calabura Fruit for Antioxidant and Cytotoxic Activities

Gayathry Muniyappan; Norfatihah Mohd Adenam; Muhamad Yuzaini Azrai MY; Nurul Hijanah MH; Daruliza Kernain; Hasyiya Karimah

doi:10.37934/araset.28.1.116125

Authors

Gayathry Muniyappan Department of Data Science, Universiti Malaysia Kelantan, City Campus, Pengkalan Chepa, Kota Bharu, 16100, Kelantan, Malaysia
Norfatihah Mohd Adenam Department of Data Science, Universiti Malaysia Kelantan, City Campus, Pengkalan Chepa, Kota Bharu, 16100, Kelantan, Malaysia
Muhamad Yuzaini Azrai MY Department of Data Science, Universiti Malaysia Kelantan, City Campus, Pengkalan Chepa, Kota Bharu, 16100, Kelantan, Malaysia
Nurul Hijanah MH Department of Data Science, Universiti Malaysia Kelantan, City Campus, Pengkalan Chepa, Kota Bharu, 16100, Kelantan, Malaysia
Daruliza Kernain Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, 11800 USM Pulau Pinang, Malaysia
Hasyiya Karimah Institute for Artificial Intelligence and Big Data, Universiti Malaysia Kelantan, City Campus, Pengkalan Chepa, 16100 Kota Bharu, Kelantan, Malaysia

DOI:

https://doi.org/10.37934/araset.28.1.116125

Keywords:

Muntingia calabura, phytochemicals, antioxidant, cytotoxicity

Abstract

Muntingia calabura (M. calabura) is an indigenous fruit species that is widely distributed in Malaysia and traditionally believed for constituting medicinal properties, yet little-known and underutilized. Hence, this study aimed to perform an extraction of M. calabura fruit to identify phytochemicals potential by carrying out several analysis such as Total Phenolic Content, Fourier Transform Infrared Spectrum (FTIR), High Performance Liquid Chromatography (HPLC) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay. Besides, the antioxidant and cytotoxicity properties of M. calabura were also identified from Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC) and brine shrimp lethality tests. The finding suggested that further study on the modification of M. calabura extraction should be carried out to explore maximal potential of M. calabura as natural medicine and commercial use .