Reducing of Thrombosis in Mechanical Heart Valve through the Computational Method: A Review

Abstract

Thrombosis isformation of a blood clot, known as a thrombus within a blood vessel. This review paper discussed thrombosis which associated with the malfunction of the heart valve based on computational method to investigate the causes of blood clotting.The non-physiological flow is thecauses oftrapped platelet andtheformation of blood clotting in the mechanical heart valve(MHV). Besides that, it isfound that the hinge design, leaflet material and flow control can reduce blood clot formation. Furthermore, a specific method to reduce thrombosis through vortex generator design on the leaflet is also discussed. Finally, the review paper providesan important critical assessment regarding the method to reduce thrombosis in mechanical heart valve for engineers, mathematician, medical doctor and scientist.