A Review on Application of Zinc Oxide Nanoparticles as Biocide, Problems of Administration, and Improved Delivery Techniques

Authors

  • Zing Neo Zhi Faculty of Applied Sciences and Technology, Universiti Tun Hussein Onn Malaysia, Pagoh Higher Education Hub, KM1 Jalan Panchor, 84600 Panchor, Johor, Malaysia
  • Ainun Rahmahwati Ainuddin Nanostructure and Surface Modification (NANOSURF), Faculty of Mechanical and Manufacturing Engineering, Universiti Tun Hussein Onn Malaysia, 86400, Parit Raja, Batu Pahat, Johor, Malaysia
  • Balkis A. Talip Faculty of Applied Sciences and Technology, Universiti Tun Hussein Onn Malaysia, Pagoh Higher Education Hub, KM1 Jalan Panchor, 84600 Panchor, Johor, Malaysia
  • Siti Aida Ibrahim Nanostructure and Surface Modification (NANOSURF), Faculty of Mechanical and Manufacturing Engineering, Universiti Tun Hussein Onn Malaysia, 86400, Parit Raja, Batu Pahat, Johor, Malaysia
  • Niki Prastomo Faculty of Engineering & Informatics, Universitas Multimedia Nusantara, Jl. Scientia Boulevard, Gading Serpong, Tangerang, Banten – 15811, Indonesia

DOI:

https://doi.org/10.37934/armne.25.1.7694

Keywords:

ZnO nanoparticle, colloidal stability, antimicrobial, effective delivery, encapsulation

Abstract

The incorporation of nanoparticles is trending in a wide range of applications for its antimicrobial properties. The antimicrobial properties, potency, and risk of ZnO nanoparticle have been assessed and justified for its efficacy in different applications. However, there is an existing gap between lab scale and on-site usage due to colloidal stability of the nanoparticles. Despite exhibiting antimicrobial properties under controlled laboratory condition, sensitivity of nanoparticles to ambient condition might reduce or negate its potency under different administered conditions. It is envisaged that encapsulation of zinc oxide nanoparticle shall improve its stability and enhance its performance as biocide. This review paper delves into the attack mechanism of ZnO nanoparticles against different bacteria, fungus, and viruses. In addition, dissolution properties and colloidal stability of nanoparticles, flaws with direct administration of nanoparticles in solid particles form and the current trend in delivery of ZnO nanoparticles were discussed to emphasize the importance of material preservation for performance maximization.

Author Biographies

Zing Neo Zhi , Faculty of Applied Sciences and Technology, Universiti Tun Hussein Onn Malaysia, Pagoh Higher Education Hub, KM1 Jalan Panchor, 84600 Panchor, Johor, Malaysia

neozhizing@gmail.com

Ainun Rahmahwati Ainuddin, Nanostructure and Surface Modification (NANOSURF), Faculty of Mechanical and Manufacturing Engineering, Universiti Tun Hussein Onn Malaysia, 86400, Parit Raja, Batu Pahat, Johor, Malaysia

ainun@uthm.edu.my

Balkis A. Talip, Faculty of Applied Sciences and Technology, Universiti Tun Hussein Onn Malaysia, Pagoh Higher Education Hub, KM1 Jalan Panchor, 84600 Panchor, Johor, Malaysia

balkis@uthm.edu.my

Siti Aida Ibrahim, Nanostructure and Surface Modification (NANOSURF), Faculty of Mechanical and Manufacturing Engineering, Universiti Tun Hussein Onn Malaysia, 86400, Parit Raja, Batu Pahat, Johor, Malaysia

saida@uthm.edu.my

Niki Prastomo, Faculty of Engineering & Informatics, Universitas Multimedia Nusantara, Jl. Scientia Boulevard, Gading Serpong, Tangerang, Banten – 15811, Indonesia

niki.prastoma@umn.ac.id

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Published

2024-11-30

How to Cite

Zhi , . . Z. N., Ainuddin, A. R. . ., A. Talip, B., Ibrahim, S. A., & Prastomo, N. . . (2024). A Review on Application of Zinc Oxide Nanoparticles as Biocide, Problems of Administration, and Improved Delivery Techniques. Journal of Advanced Research in Micro and Nano Engineering, 25(1), 76–94. https://doi.org/10.37934/armne.25.1.7694

Issue

Vol. 25 No. 1: November (2024)

Section

Articles