Synthesis and Characterization of New Choline-Based Ionic Liquids and Their Antimicrobial Properties

Authors

  • Haslina Ahmad Department of Chemistry, Faculty Science, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
  • Nurul Syahira Zaharudin Department of Chemistry, Faculty Science, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
  • Nur Nadia Abdul Majid Department of Chemistry, Faculty Science, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
  • Khairulazhar Jumbri Centre of Research in Ionic Liquids, Universiti Teknologi PETRONAS, 32610 Seri Iskandar, P
  • Mohd Basyaruddin Abdul Rahman Department of Chemistry, Faculty Science, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia

Keywords:

Ionic liquids , antimicrobial , cholinium , neutralization reaction

Abstract

A series of new cholinium-based ionic liquids (ILs) was synthesized by using simple neutralization reaction. The synthesized ILs were choline phenylacetate, choline ricinoleate and choline trichloroacetate. Result obtained from FT-IR, 1H and 13C NMR, mass spectrometry, thermogravimetric and differential scanning calorimetry confirmed the formation of these cholinium-based ILs. These ILs were then tested for their anti-microbial properties towards seven types of bacteria which consist of three Gram-positive bacteria, Bacillus subtilis (B29), Staphylococcus aureus (S276), Staphylococcus epidermidis (S273), two Gram-negative bacteria, Pseudomonas aeruginosa (ATCC 15442) and Escherichia coli (E266) and two types of yeasts, Candida albicans (9002) and Candida tropicalis (A3).Interestingly, all of the choliniumILs possess excellent antimicrobial activity as good as the standard, Streptomycin. The most significant antimicrobial activity was observed in choline phenylacetate against all seven types of bacteria tested in this study.

Downloads

Download data is not yet available.

Downloads

Published

2024-03-28

How to Cite

Haslina Ahmad, Nurul Syahira Zaharudin, Nur Nadia Abdul Majid, Khairulazhar Jumbri, & Mohd Basyaruddin Abdul Rahman. (2024). Synthesis and Characterization of New Choline-Based Ionic Liquids and Their Antimicrobial Properties. Journal of Advanced Research in Fluid Mechanics and Thermal Sciences, 54(2), 124–132. Retrieved from https://semarakilmu.com.my/journals/index.php/fluid_mechanics_thermal_sciences/article/view/3034

Issue

Section

Articles

Similar Articles

You may also start an advanced similarity search for this article.