Fluid-Structure Interaction Modelling of Blood Flow in Peripheral Arterial Disease

Authors

  • Muhammad Firdaus Mohd Fauzi Faculty of Mechanical and Automotive Engineering Technology, Universiti Malaysia Pahang Al-Sultan Abdullah, 26600 Pekan, Pahang, Malaysia
  • Nasrul Hadi Johari Faculty of Mechanical and Automotive Engineering Technology, Universiti Malaysia Pahang Al-Sultan Abdullah, 26600 Pekan, Pahang, Malaysia
  • Mohd Jamil Mohamed Mokhtarudin Faculty of Manufacturing and Mechatronics Engineering Technology, Universiti Malaysia Pahang Al-Sultan Abdullah, 26600 Pekan, Pahang, Malaysia
  • Bazli Mohd Yusoff Department of Radiology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, 16150 Kota Bharu, Kelantan, Malaysia
  • Baolei Guo Department of Vascular Surgery, Institute of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

DOI:

https://doi.org/10.37934/arfmts.119.1.117133

Keywords:

Peripheral arterial disease, fluid-structure interaction, atherosclerosis, hemodynamics

Abstract

The study presents the fluid-structure interaction (FSI) modeling in Peripheral Arterial Disease (PAD) geometry, highlighting the effects of arterial blockage on hemodynamics and arterial wall mechanics. Employing a RANS-based SST-Tran model, the study examines stenotic PAD models under realistic boundary conditions, coupled with a hyperelastic Mooney-Rivlin model to simulate the arterial wall's response. The analysis includes velocity profiles, wall shear stress (WSS), pressure distribution, and wall displacement, revealing significant differences between healthy and stenosed models. It demonstrates adaptive hemodynamics, the impact of stenosis on flow mechanics, and potential implications for atherosclerosis and plaque formation. The findings highlight the importance of understanding stenosis severity for clinical risk assessment, treatment planning, and monitoring.

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Author Biographies

Muhammad Firdaus Mohd Fauzi, Faculty of Mechanical and Automotive Engineering Technology, Universiti Malaysia Pahang Al-Sultan Abdullah, 26600 Pekan, Pahang, Malaysia

firdaus0124@gmail.com

Nasrul Hadi Johari, Faculty of Mechanical and Automotive Engineering Technology, Universiti Malaysia Pahang Al-Sultan Abdullah, 26600 Pekan, Pahang, Malaysia

nhadi@umpsa.edu.my

Mohd Jamil Mohamed Mokhtarudin, Faculty of Manufacturing and Mechatronics Engineering Technology, Universiti Malaysia Pahang Al-Sultan Abdullah, 26600 Pekan, Pahang, Malaysia

mohdjamil@ump.edu.my

Bazli Mohd Yusoff, Department of Radiology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, 16150 Kota Bharu, Kelantan, Malaysia

bazliyusoff@usm.my

Baolei Guo, Department of Vascular Surgery, Institute of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

guo.baolei@zs-hospital.sh.cn

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Published

2024-07-15

How to Cite

Muhammad Firdaus Mohd Fauzi, Nasrul Hadi Johari, Mohd Jamil Mohamed Mokhtarudin, Bazli Mohd Yusoff, & Baolei Guo. (2024). Fluid-Structure Interaction Modelling of Blood Flow in Peripheral Arterial Disease. Journal of Advanced Research in Fluid Mechanics and Thermal Sciences, 119(1), 117–133. https://doi.org/10.37934/arfmts.119.1.117133

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